Title : Phospholipase D is involved in oxidative stress-induced migration of vascular smooth muscle cells via tyrosine phosphorylation and protein kinase C.

Pub. Date : 2004 Apr 30

PMID : 15150437






7 Functional Relationships(s)
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1 In the presence of vanadate, H(2)O(2) induced tyrosine phosphorylation of PLD1, protein kinase C-alpha (PKC-alpha), and other unidentified proteins in rat vascular smooth muscle cells (VSMCs). Vanadates phospholipase D1 Rattus norvegicus
2 In the presence of vanadate, H(2)O(2) induced tyrosine phosphorylation of PLD1, protein kinase C-alpha (PKC-alpha), and other unidentified proteins in rat vascular smooth muscle cells (VSMCs). Hydrogen Peroxide phospholipase D1 Rattus norvegicus
3 In the presence of vanadate, H(2)O(2) induced tyrosine phosphorylation of PLD1, protein kinase C-alpha (PKC-alpha), and other unidentified proteins in rat vascular smooth muscle cells (VSMCs). Tyrosine phospholipase D1 Rattus norvegicus
4 Interestingly, PLD1 was found to be constitutively associated with PKC-alpha in VSMCs. vsmcs phospholipase D1 Rattus norvegicus
5 Stimulation of the cells by H(2)O(2) and vanadate showed a concentration-dependent tyrosine phosphorylation of the proteins in PLD1 immunoprecipitates and activation of PLD. Hydrogen Peroxide phospholipase D1 Rattus norvegicus
6 Stimulation of the cells by H(2)O(2) and vanadate showed a concentration-dependent tyrosine phosphorylation of the proteins in PLD1 immunoprecipitates and activation of PLD. Vanadates phospholipase D1 Rattus norvegicus
7 Stimulation of the cells by H(2)O(2) and vanadate showed a concentration-dependent tyrosine phosphorylation of the proteins in PLD1 immunoprecipitates and activation of PLD. Tyrosine phospholipase D1 Rattus norvegicus