Pub. Date : 2004 Jun 4
PMID : 15144894
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We previously reported that mice lacking bombesin receptor subtype-3 (BRS-3) exhibit mild late-onset obesity and glucose intolerance [Nature 390 (1997) 160]. | Glucose | bombesin-like receptor 3 | Mus musculus |
2 | We previously reported that mice lacking bombesin receptor subtype-3 (BRS-3) exhibit mild late-onset obesity and glucose intolerance [Nature 390 (1997) 160]. | Glucose | bombesin-like receptor 3 | Mus musculus |
3 | In contrast, adipose tissues exhibited a marked difference: the uptake of [(14)C]2-deoxy-D-glucose by adipocytes isolated from BRS-3-deficient mice was not stimulated by 10(-7)M insulin addition, and membrane fractionation analysis showed that GLUT4 was barely detected in the fraction of plasma membrane in BRS-3-deficient mice in the presence of 10(-7)M insulin. | Deoxyglucose | bombesin-like receptor 3 | Mus musculus |