Title : Pharmacological rescue of trafficking defective HERG channels formed by coassembly of wild-type and long QT mutant N470D subunits.

Pub. Date : 2004 Aug

PMID : 15072950






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We previously showed that the HERG N470D mutation expressed as homotetrameric channels causes a protein trafficking defect, and this can be corrected by the HERG channel blocking drug E-4031. E 4031 potassium voltage-gated channel subfamily H member 2 Homo sapiens
2 We previously showed that the HERG N470D mutation expressed as homotetrameric channels causes a protein trafficking defect, and this can be corrected by the HERG channel blocking drug E-4031. E 4031 potassium voltage-gated channel subfamily H member 2 Homo sapiens