Title : Aquaporins in skeletal muscle: reassessment of the functional role of aquaporin-4.

Pub. Date : 2004 May

PMID : 15033928






5 Functional Relationships(s)
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Protein Name
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1 Aquaporin-4 (AQP4) is the major water channel of the neuromuscular system, but its physiological function in both perivascular astrocytes and skeletal muscle sarcolemma is unclear. Water aquaporin 4 Mus musculus
2 Aquaporin-4 (AQP4) is the major water channel of the neuromuscular system, but its physiological function in both perivascular astrocytes and skeletal muscle sarcolemma is unclear. Water aquaporin 4 Mus musculus
3 Sarcolemma vesicles prepared from mdx mice revealed, in parallel with AQP4 disappearance from the plasma membrane, a strong reduction in water permeability compared with wild-type mice. Water aquaporin 4 Mus musculus
4 Altogether, these results demonstrate high AQP4-mediated water permeability of the skeletal muscle sarcolemma. Water aquaporin 4 Mus musculus
5 Expression of sarcolemmal AQP4 together with that of vascular AQP1 may be responsible for the fast water transfer from the blood into the muscle during intense activity. Water aquaporin 4 Mus musculus