Title : Pheophorbide a is a specific probe for ABCG2 function and inhibition.

Pub. Date : 2004 Feb 15

PMID : 14973080






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Pheophorbide a (PhA), a chlorophyll catabolite, was shown to be an ABCG2 substrate based on Abcg2(-/-) knockout mouse studies (J. W. Jonker et al., Proc. pheophorbide a lamin B receptor Homo sapiens
2 Pheophorbide a (PhA), a chlorophyll catabolite, was shown to be an ABCG2 substrate based on Abcg2(-/-) knockout mouse studies (J. W. Jonker et al., Proc. chlorophyll catabolite lamin B receptor Homo sapiens
3 We found that 100 micro M of the cyclin-dependent kinase inhibitor UCN-01 or 1 micro M of the P-glycoprotein inhibitor tariquidar inhibited ABCG2-mediated PhA transport. 7-hydroxystaurosporine lamin B receptor Homo sapiens
4 We found that 100 micro M of the cyclin-dependent kinase inhibitor UCN-01 or 1 micro M of the P-glycoprotein inhibitor tariquidar inhibited ABCG2-mediated PhA transport. tariquidar lamin B receptor Homo sapiens