Title : A mild and efficient procedure for alpha-bromination of ketones using N-bromosuccinimide catalysed by ammonium acetate.

Pub. Date : 2004 Feb 21

PMID : 14765263






1 Functional Relationships(s)
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1 Cyclic ketones reacted with N-bromosuccinimide (NBS) catalysed by NH(4)OAc in Et(2)O at 25 degrees C to give the corresponding alpha-brominated ketones in good yields, while acyclic ketones were efficiently brominated in CCl(4) at 80 degrees C. ammonium acetate nibrin Homo sapiens