Pub. Date : 2004 Feb 15
PMID : 14759599
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Azide binding to yeast cytochrome c peroxidase and horse metmyoglobin: comparative thermodynamic investigation using isothermal titration calorimetry. | Azides | cytochrome-c peroxidase | Saccharomyces cerevisiae S288C |
| 2 | CcP and Mb differ significantly in their reactivity toward the azide anion, N3-. | Azides | cytochrome-c peroxidase | Saccharomyces cerevisiae S288C |
| 3 | Protonation of His-64 in Mb enhances HN3 binding due to a gating mechanism while protonation of His-52 in CcP decreases the affinity for HN3 due to loss of base-assisted association of the ligand to the heme iron. | Histidine | cytochrome-c peroxidase | Saccharomyces cerevisiae S288C |
| 4 | Protonation of His-64 in Mb enhances HN3 binding due to a gating mechanism while protonation of His-52 in CcP decreases the affinity for HN3 due to loss of base-assisted association of the ligand to the heme iron. | Iron | cytochrome-c peroxidase | Saccharomyces cerevisiae S288C |