Pub. Date : 2004 Jan
PMID : 14752829
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | AQP4 transfected into mouse cholangiocytes promotes water transport in biliary epithelia. | Water | aquaporin 4 | Mus musculus |
2 | In this study, we established a novel AQP4-transfected polarized mouse cholangiocyte cell line suitable for functional studies of transepithelial water transport, and, using this model, we define the importance of this AQP in water transport across biliary epithelia. | Water | aquaporin 4 | Mus musculus |
3 | In this study, we established a novel AQP4-transfected polarized mouse cholangiocyte cell line suitable for functional studies of transepithelial water transport, and, using this model, we define the importance of this AQP in water transport across biliary epithelia. | Water | aquaporin 4 | Mus musculus |
4 | In NMCs transfected with AQP4, P(f) increased to 75.7 +/- 1.4 microm/sec, that is, by 4.6-fold, indicating the contribution of AQP4 in channel-mediated water transport across MNCs monolayer. | Water | aquaporin 4 | Mus musculus |
5 | In NMCs transfected with AQP4, P(f) increased to 75.7 +/- 1.4 microm/sec, that is, by 4.6-fold, indicating the contribution of AQP4 in channel-mediated water transport across MNCs monolayer. | Water | aquaporin 4 | Mus musculus |
6 | In conclusion, we developed a novel polarized mouse cholangiocyte monolayer model, allowing direct study of AQP4-mediated water transport by biliary epithelia and generated data providing additional support for the importance of AQP4 in cholangiocyte water transport. | Water | aquaporin 4 | Mus musculus |