Pub. Date : 2003 Dec
PMID : 14750024
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Sauchinone, a lignan from Saururus chinensis, suppresses iNOS expression through the inhibition of transactivation activity of RelA of NF-kappaB. | sauchinone | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | Mus musculus |
| 2 | Further analysis revealed that transactivation activity of RelA subunit of NF-kappaB was dose-dependently suppressed in the presence of sauchinone. | sauchinone | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | Mus musculus |
| 3 | Taken together, our results suggested that sauchinone could inhibit production of NO in LPS-stimulated RAW264.7 cells through the suppression of NF-kappaB by inhibiting transactivation activity of RelA subunit. | sauchinone | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | Mus musculus |