Title : B-endorphin response to a low dosage of human corticotropin releasing hormone during metyrapone administration in depression.

Pub. Date : 1992

PMID : 1473519






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1 B-endorphin response to a low dosage of human corticotropin releasing hormone during metyrapone administration in depression. Metyrapone corticotropin releasing hormone Homo sapiens
2 This study defines the pituitary B-endorphin (BE) secretory response to a low dosage (0.3 ug/kg) of human corticotropin releasing hormone (CRH) in depressed patients and normal controls pretreated with metyrapone. Metyrapone corticotropin releasing hormone Homo sapiens
3 The influence of metyrapone pretreatment on the pituitary B-endorphin response to CRH through a mechanism that minimizes the impact of cortisol negative feedback is discussed. Metyrapone corticotropin releasing hormone Homo sapiens