Title : Some 1,2-diphenylethane derivatives as inhibitors of retinoic acid--metabolising enzymes.

Pub. Date : 2003 Oct

PMID : 14692511






2 Functional Relationships(s)
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1 Several of the compounds were weak inhibitors of the non-specific rat liver microsomal P450 enzymes and moderate inhibitors of the RA-induced enzymes in cultured human genital fibroblasts, where the RA-specific enzyme CYP26 is probably expressed. Radium cytochrome P450 family 26 subfamily A member 1 Homo sapiens
2 Several of the compounds were weak inhibitors of the non-specific rat liver microsomal P450 enzymes and moderate inhibitors of the RA-induced enzymes in cultured human genital fibroblasts, where the RA-specific enzyme CYP26 is probably expressed. Radium cytochrome P450 family 26 subfamily A member 1 Homo sapiens