Title : Effects of the proteasome inhibitor, bortezomib, on apoptosis in isolated lymphocytes obtained from patients with chronic lymphocytic leukemia.

Pub. Date : 2003 Oct 1

PMID : 14555532






2 Functional Relationships(s)
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1 Bortezomib-induced apoptosis was associated with release of SMAC, apoptosis-inducing factor, and cytochrome c from mitochondria, but the drug did not affect levels of inhibitor of apoptosis protein family cell death inhibitors. Bortezomib diablo IAP-binding mitochondrial protein Homo sapiens
2 Bortezomib-induced apoptosis was associated with release of SMAC, apoptosis-inducing factor, and cytochrome c from mitochondria, but the drug did not affect levels of inhibitor of apoptosis protein family cell death inhibitors. Bortezomib cytochrome c, somatic Homo sapiens