Title : Amino acid starvation and Gcn4p regulate adhesive growth and FLO11 gene expression in Saccharomyces cerevisiae.

Pub. Date : 2003 Oct

PMID : 14517335






5 Functional Relationships(s)
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1 These morphogenetic events are induced by starvation for glucose or nitrogen and require the cell surface protein Flo11p. Glucose Flo11p Saccharomyces cerevisiae S288C
2 We show that amino acid starvation is a nutritional signal that activates adhesive growth and expression of FLO11 in both haploid and diploid strains in the presence of glucose and ammonium, known suppressors of adhesion. Glucose Flo11p Saccharomyces cerevisiae S288C
3 We show that amino acid starvation is a nutritional signal that activates adhesive growth and expression of FLO11 in both haploid and diploid strains in the presence of glucose and ammonium, known suppressors of adhesion. Ammonium Compounds Flo11p Saccharomyces cerevisiae S288C
4 Promoter analysis of FLO11 identifies one upstream activation sequence (UASR) and one repression site (URS) that confer regulation by amino acid starvation. Peptichemio Flo11p Saccharomyces cerevisiae S288C
5 Gcn4p is not required for regulation of the UASR by amino acid starvation, but seems to be indirectly required to overcome the negative effects of the URS on FLO11 transcription. Peptichemio Flo11p Saccharomyces cerevisiae S288C