Title : Antisense oligonucleotide eliminates in vivo expression of c-fos in mammalian brain.

Pub. Date : 1992 Dec 1

PMID : 1446715






6 Functional Relationships(s)
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1 Antisense oligonucleotide eliminates in vivo expression of c-fos in mammalian brain. Oligonucleotides Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens
2 Immediate-early genes such as c-fos and NGFI-A are rapidly and transiently expressed in the striatum following amphetamine administration in vivo. Amphetamine Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens
3 Here we show that direct infusion of an antisense oligodeoxynucleotide to c-fos into striatum will reduce amphetamine-induced production of Fos-like immunoreactivity without affecting NGFI-A expression. Oligodeoxyribonucleotides Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens
4 Here we show that direct infusion of an antisense oligodeoxynucleotide to c-fos into striatum will reduce amphetamine-induced production of Fos-like immunoreactivity without affecting NGFI-A expression. Oligodeoxyribonucleotides Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens
5 Here we show that direct infusion of an antisense oligodeoxynucleotide to c-fos into striatum will reduce amphetamine-induced production of Fos-like immunoreactivity without affecting NGFI-A expression. Amphetamine Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens
6 Here we show that direct infusion of an antisense oligodeoxynucleotide to c-fos into striatum will reduce amphetamine-induced production of Fos-like immunoreactivity without affecting NGFI-A expression. Amphetamine Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens