Title : Cell proliferation and protooncogene induction in oligodendroglial progenitors.

Pub. Date : 1992 Jul

PMID : 1433384






4 Functional Relationships(s)
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1 The induction of c-fos gene expression and DNA synthesis in response to PMA was completely blocked by 1-(5-isoquinolinyl-sulfonyl)-2-methylpiperazine (H-7), a potent inhibitor of protein kinase C (PKC), thereby suggesting a role for PKC in the control of c-fos expression and cell proliferation in OL progenitors. 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens
2 The induction of c-fos gene expression and DNA synthesis in response to PMA was completely blocked by 1-(5-isoquinolinyl-sulfonyl)-2-methylpiperazine (H-7), a potent inhibitor of protein kinase C (PKC), thereby suggesting a role for PKC in the control of c-fos expression and cell proliferation in OL progenitors. 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens
3 The induction of c-fos gene expression and DNA synthesis in response to PMA was completely blocked by 1-(5-isoquinolinyl-sulfonyl)-2-methylpiperazine (H-7), a potent inhibitor of protein kinase C (PKC), thereby suggesting a role for PKC in the control of c-fos expression and cell proliferation in OL progenitors. 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens
4 The induction of c-fos gene expression and DNA synthesis in response to PMA was completely blocked by 1-(5-isoquinolinyl-sulfonyl)-2-methylpiperazine (H-7), a potent inhibitor of protein kinase C (PKC), thereby suggesting a role for PKC in the control of c-fos expression and cell proliferation in OL progenitors. 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens