Title : ERCC1 and ERCC2 expression in malignant tissues from ovarian cancer patients.

Pub. Date : 1992 Oct 7

PMID : 1433335






2 Functional Relationships(s)
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1 RESULTS: Patients who were clinically resistant to platinum-based therapy had a 2.6-fold higher expression level of ERCC1 in their tumor tissue than did patients who responded to that therapy (P = .015). Platinum ERCC excision repair 1, endonuclease non-catalytic subunit Homo sapiens
2 CONCLUSION: We conclude that ERCC1 expression levels in human tumor tissue may have a role in clinical resistance to platinum compounds. Platinum ERCC excision repair 1, endonuclease non-catalytic subunit Homo sapiens