Title : Regulation of genetic expression in shear stress-stimulated endothelial cells.

Pub. Date : 1992 Oct 13

PMID : 1416623






2 Functional Relationships(s)
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1 Because agonist-induced modulations in the rate of synthesis of tPA and ET have been associated with the Fos and Jun protein families, it seems reasonable to propose that genetic expression in shear stress- or mechanical strain-stimulated endothelial cells is also regulated by selective induction of fos and jun gene products. Tetradecanoylphorbol Acetate Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens
2 Because agonist-induced modulations in the rate of synthesis of tPA and ET have been associated with the Fos and Jun protein families, it seems reasonable to propose that genetic expression in shear stress- or mechanical strain-stimulated endothelial cells is also regulated by selective induction of fos and jun gene products. Tetradecanoylphorbol Acetate Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens