Title : Interactions among LRF-1, JunB, c-Jun, and c-Fos define a regulatory program in the G1 phase of liver regeneration.

Pub. Date : 1992 Oct

PMID : 1406655






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 LRF-1 in combination with either Jun protein strongly activates a cyclic AMP response element-containing promoter which c-Fos/Jun does not activate. Cyclic AMP Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens
2 As the relative level of LRF-1/JunB complexes increases posthepatectomy, c-Fos/Jun-mediated ATF and AP-1 site activation is likely to decrease with simultaneous transcriptional activation of the many liver-specific genes whose promoters contain cyclic AMP response element sites. Cyclic AMP Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens