Title : Constitutive expression of AP-1 transcription factors in the rat adrenal. Effects of nicotine.

Pub. Date : 1992 Oct 5

PMID : 1400333






2 Functional Relationships(s)
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1 Handling of rats for several days prior to sacrifice failed to affect protein expression or binding; on the other hand, repeated injections of nicotine increased AP-1 DNA binding. Nicotine Jun proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus
2 A single nicotine injection 60 min prior to removing the adrenals caused a significant reduction in AP-1 DNA binding without any detectable changes in AP-1 protein expression. Nicotine Jun proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus