Title : Scopolamine attenuates haloperidol-induced c-fos expression in the striatum.

Pub. Date : 1992 Aug 14

PMID : 1393566






9 Functional Relationships(s)
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1 Scopolamine attenuates haloperidol-induced c-fos expression in the striatum. Scopolamine Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens
2 Scopolamine attenuates haloperidol-induced c-fos expression in the striatum. Haloperidol Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens
3 Haloperidol increases the expression of Fos, the protein product of the proto-oncogene c-fos, in some parts of the central nervous system. Haloperidol Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens
4 Haloperidol increases the expression of Fos, the protein product of the proto-oncogene c-fos, in some parts of the central nervous system. Haloperidol Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens
5 In order to gain insight into the neurochemical and neuroanatomical substrates of haloperidol-induced catalepsy we examined the effects of the muscarinic receptor antagonist scopolamine on haloperidol-induced Fos expression in the striatum, nucleus accumbens and lateral septal nucleus. Scopolamine Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens
6 In order to gain insight into the neurochemical and neuroanatomical substrates of haloperidol-induced catalepsy we examined the effects of the muscarinic receptor antagonist scopolamine on haloperidol-induced Fos expression in the striatum, nucleus accumbens and lateral septal nucleus. Haloperidol Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens
7 At a dose that reduced the cataleptic effect of haloperidol, scopolamine decreased the neuroleptic-induced Fos expression in the striatum and lateral septal nucleus but not the nucleus accumbens. Haloperidol Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens
8 At a dose that reduced the cataleptic effect of haloperidol, scopolamine decreased the neuroleptic-induced Fos expression in the striatum and lateral septal nucleus but not the nucleus accumbens. Scopolamine Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens
9 These results indicate that haloperidol may increase c-fos expression in medium spiny striatal neurons indirectly by enhancing striatal acetylcholine release. Haloperidol Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens