Pub. Date : 1992 Apr 1
PMID : 1372530
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Hydroxyl radicals may play a role in the induction mechanism since dimethyl sulfoxide, a radical scavenger, blocked the radiation-mediated increase in MGMT. | Hydroxyl Radical | O-6-methylguanine-DNA methyltransferase | Rattus norvegicus |
| 2 | Hydroxyl radicals may play a role in the induction mechanism since dimethyl sulfoxide, a radical scavenger, blocked the radiation-mediated increase in MGMT. | Dimethyl Sulfoxide | O-6-methylguanine-DNA methyltransferase | Rattus norvegicus |
| 3 | MGMT activity was also increased by treatment of the cells with H2O2, in accordance with the involvement of activated oxygen species in the induction of MGMT. | Hydrogen Peroxide | O-6-methylguanine-DNA methyltransferase | Rattus norvegicus |
| 4 | MGMT activity was also increased by treatment of the cells with H2O2, in accordance with the involvement of activated oxygen species in the induction of MGMT. | Hydrogen Peroxide | O-6-methylguanine-DNA methyltransferase | Rattus norvegicus |
| 5 | MGMT activity was also increased by treatment of the cells with H2O2, in accordance with the involvement of activated oxygen species in the induction of MGMT. | Oxygen | O-6-methylguanine-DNA methyltransferase | Rattus norvegicus |
| 6 | MGMT activity was also increased by treatment of the cells with H2O2, in accordance with the involvement of activated oxygen species in the induction of MGMT. | Oxygen | O-6-methylguanine-DNA methyltransferase | Rattus norvegicus |
| 7 | Finally, the addition of cycloheximide, an inhibitor of protein synthesis, prior to but not after irradiation, abolished the increase in MGMT activity. | Cycloheximide | O-6-methylguanine-DNA methyltransferase | Rattus norvegicus |