Title : Active oxygen species stimulate vascular smooth muscle cell growth and proto-oncogene expression.

Pub. Date : 1992 Mar

PMID : 1371430






2 Functional Relationships(s)
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1 H2O2 (200 microM) stimulated c-myc and c-fos mRNA levels by fourfold and 20-fold, respectively, as compared with quiescent levels. Hydrogen Peroxide Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens
2 In contrast to DNA synthesis, H2O2 induction of c-myc and c-fos mRNA was primarily protein kinase C dependent. Hydrogen Peroxide Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens