Title : Monocyte chemoattractant protein-1 (MCP-1) expression in human articular cartilage. Induction by peptide regulatory factors and differential effects of dexamethasone and retinoic acid.

Pub. Date : 1992 Aug

PMID : 1365641






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Dexamethasone blunted the induction of MCP-1 gene expression by IL-1 and by activators of protein kinase A as well as protein kinase C signal transduction pathways. Dexamethasone C-C motif chemokine ligand 2 Homo sapiens
2 In contrast, retinoic acid strongly increased phorbol myristate acetate-induced MCP-1 expression and potentiated the effects of IL-1 and LPS. Tretinoin C-C motif chemokine ligand 2 Homo sapiens
3 In contrast, retinoic acid strongly increased phorbol myristate acetate-induced MCP-1 expression and potentiated the effects of IL-1 and LPS. Tetradecanoylphorbol Acetate C-C motif chemokine ligand 2 Homo sapiens