Title : Exogenous retinoic acid rapidly induces anterior ectopic expression of murine Hox-2 genes in vivo.

Pub. Date : 1992 Oct

PMID : 1363087






5 Functional Relationships(s)
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1 Exogenous retinoic acid rapidly induces anterior ectopic expression of murine Hox-2 genes in vivo. Tretinoin homeobox B cluster Mus musculus
2 The ectopic expression of the 3" Hox-2 genes in response to RA is consistent with a role for these genes in mediating the teratogenic effects of RA; the rapid response of the Hox-C genes to RA is consistent with a role for endogenous RA in refining 3" Hox-C gene expression boundaries early in development. Tretinoin homeobox B cluster Mus musculus
3 The ectopic expression of the 3" Hox-2 genes in response to RA is consistent with a role for these genes in mediating the teratogenic effects of RA; the rapid response of the Hox-C genes to RA is consistent with a role for endogenous RA in refining 3" Hox-C gene expression boundaries early in development. Tretinoin homeobox B cluster Mus musculus
4 The ectopic expression of the 3" Hox-2 genes in response to RA is consistent with a role for these genes in mediating the teratogenic effects of RA; the rapid response of the Hox-C genes to RA is consistent with a role for endogenous RA in refining 3" Hox-C gene expression boundaries early in development. Tretinoin homeobox B cluster Mus musculus
5 The ectopic expression of the 3" Hox-2 genes in response to RA is consistent with a role for these genes in mediating the teratogenic effects of RA; the rapid response of the Hox-C genes to RA is consistent with a role for endogenous RA in refining 3" Hox-C gene expression boundaries early in development. Tretinoin homeobox B cluster Mus musculus