Pub. Date : 1992 Jun
PMID : 1338333
13 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Elevated cAMP is required for stimulation of eicosanoid synthesis by interleukin 1 and bradykinin in BALB/c 3T3 fibroblasts. | Cyclic AMP | interleukin 1 complex | Mus musculus |
| 2 | Elevated cAMP is required for stimulation of eicosanoid synthesis by interleukin 1 and bradykinin in BALB/c 3T3 fibroblasts. | Eicosanoids | interleukin 1 complex | Mus musculus |
| 3 | In Swiss 3T3 murine fibroblasts, interleukin 1 (IL-1) and bradykinin stimulate prostaglandin E2 (PGE2) synthesis. | Dinoprostone | interleukin 1 complex | Mus musculus |
| 4 | In Swiss 3T3 murine fibroblasts, interleukin 1 (IL-1) and bradykinin stimulate prostaglandin E2 (PGE2) synthesis. | Dinoprostone | interleukin 1 complex | Mus musculus |
| 5 | When BALB/c 3T3 cells were preincubated with cAMP analogs, both IL-1 and bradykinin stimulated PGE2 synthesis to levels similar to those observed in Swiss 3T3 cells. | Cyclic AMP | interleukin 1 complex | Mus musculus |
| 6 | When BALB/c 3T3 cells were preincubated with cAMP analogs, both IL-1 and bradykinin stimulated PGE2 synthesis to levels similar to those observed in Swiss 3T3 cells. | Dinoprostone | interleukin 1 complex | Mus musculus |
| 7 | Similarly, when the cells were preincubated with forskolin, which activates the catalytic subunit of adenylate cyclase directly, or NECA, which stimulates cellular cAMP accumulation by activating adenosine receptors, IL-1 and bradykinin stimulated PGE2 synthesis. | Colforsin | interleukin 1 complex | Mus musculus |
| 8 | Similarly, when the cells were preincubated with forskolin, which activates the catalytic subunit of adenylate cyclase directly, or NECA, which stimulates cellular cAMP accumulation by activating adenosine receptors, IL-1 and bradykinin stimulated PGE2 synthesis. | Cyclic AMP | interleukin 1 complex | Mus musculus |
| 9 | Rp-cAMPS, an inhibitor of cAMP-dependent protein kinase, blocked the ability of cAMP or NECA to render cells responsive to IL-1 and bradykinin. | Cyclic AMP | interleukin 1 complex | Mus musculus |
| 10 | Rp-cAMPS, an inhibitor of cAMP-dependent protein kinase, blocked the ability of cAMP or NECA to render cells responsive to IL-1 and bradykinin. | Adenosine-5'-(N-ethylcarboxamide) | interleukin 1 complex | Mus musculus |
| 11 | In basal BALB/c 3T3 cells, bradykinin and IL-1 stimulated arachidonate release in the absence of cAMP, but little conversion of released arachidonate to PGE2 occurred. | Arachidonic Acid | interleukin 1 complex | Mus musculus |
| 12 | In these cells, IL-1 and bradykinin stimulated PGE2 synthesis despite basal intracellular cAMP concentrations similar to BALB/c, and cAMP only modestly potentiated the response. | Dinoprostone | interleukin 1 complex | Mus musculus |
| 13 | In these cells, IL-1 and bradykinin stimulated PGE2 synthesis despite basal intracellular cAMP concentrations similar to BALB/c, and cAMP only modestly potentiated the response. | Cyclic AMP | interleukin 1 complex | Mus musculus |