Pub. Date : 1992 Nov 2
PMID : 1335418
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Activation of protein kinase C and elevation of cAMP interact synergistically to raise c-Fos and AP-1 activity in Jurkat cells. | Cyclic AMP | Fos proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |
| 2 | PMA treatment caused a concentration- and time-dependent increase in both c-Fos and Jun immunoreactivity in contrast to cAMP elevation that had only a slight effect. | Tetradecanoylphorbol Acetate | Fos proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |
| 3 | Both PMA and the combination of NECA and forskolin acted together either to increase (c-Fos) or decrease (Jun) protein levels as well as increasing AP-1 binding, as judged by gel-shift assay, and AP-1 transcriptional activity. | Colforsin | Fos proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |