Title : Differences in regulation of gene expression between Cyp1a-1 and Cyp1a-2 in adult mouse hepatocytes in primary culture.

Pub. Date : 1992 Dec

PMID : 1335375






4 Functional Relationships(s)
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1 The expression of 3-methylcholanthrene (MCA)-induced CYP1A1 mRNA remained high during the observation period under both monolayer and spheroid culture conditions. Methylcholanthrene cytochrome P450, family 1, subfamily a, polypeptide 1 Mus musculus
2 The expression of 3-methylcholanthrene (MCA)-induced CYP1A1 mRNA remained high during the observation period under both monolayer and spheroid culture conditions. Methylcholanthrene cytochrome P450, family 1, subfamily a, polypeptide 1 Mus musculus
3 An increase in intracellular cyclic nucleotide content induced CYP1A1 mRNA in the later culture period in either spheroid or monolayer cultures. Nucleotides, Cyclic cytochrome P450, family 1, subfamily a, polypeptide 1 Mus musculus
4 The level of CYP1A1 mRNA after MCA treatment was elevated in the presence of cycloheximide. Cycloheximide cytochrome P450, family 1, subfamily a, polypeptide 1 Mus musculus