Title : Opposing actions of Fos and Jun on transcription of the phosphoenolpyruvate carboxykinase (GTP) gene. Dominant negative regulation by Fos.

Pub. Date : 1992 Sep 5

PMID : 1325459






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Stimulation of PEPCK transcription by 8-Br-cAMP or by overexpression of the catalytic subunit of protein kinase A was inhibited by Fos expression. 8-Bromo Cyclic Adenosine Monophosphate Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens
2 The inhibitory effects of phorbol esters and protein kinase C on PEPCK gene expression may be mediated through the action of Fos and Jun. Phorbol Esters Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens