Title : The role of pancreatic hormones in the regulation of lipid storage, oxidation and secretion in primary cultures of rat hepatocytes. Short- and long-term effects.

Pub. Date : 1992 Jan 15

PMID : 1310593






4 Functional Relationships(s)
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1 Exposure of cultured rat hepatocytes to a high concentration of insulin (78 nM) for 24 h in the presence of extracellular oleate (0.75 mM) resulted in a decrease in the secretion of apoprotein B (apoB) and triacylglycerol associated with very-low-density lipoprotein (VLDL). Oleic Acid apolipoprotein B Rattus norvegicus
2 Exposure of cultured rat hepatocytes to a high concentration of insulin (78 nM) for 24 h in the presence of extracellular oleate (0.75 mM) resulted in a decrease in the secretion of apoprotein B (apoB) and triacylglycerol associated with very-low-density lipoprotein (VLDL). Oleic Acid apolipoprotein B Rattus norvegicus
3 Exposure of cultured rat hepatocytes to a high concentration of insulin (78 nM) for 24 h in the presence of extracellular oleate (0.75 mM) resulted in a decrease in the secretion of apoprotein B (apoB) and triacylglycerol associated with very-low-density lipoprotein (VLDL). Triglycerides apolipoprotein B Rattus norvegicus
4 Treatment of hepatocytes with glucagon (0.1 microM) for 24 h also suppressed the secretion of VLDL apoB, cholesterol and triacylglycerol. Glucagon apolipoprotein B Rattus norvegicus