Pub. Date : 1992 Feb
PMID : 1310090
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In vivo primer extension analysis indicated that this control is complex and involves both positive and negative effects by cyclic AMP-CRP on multiple ompB promoters. | Cyclic AMP | catabolite gene activator protein | Escherichia coli |
2 | In vitro footprinting showed that cyclic AMP-CRP binds to a 34-bp site centered at -53 and at -75 in relation to the start sites of the major transcripts that are inhibited and activated, respectively, by this complex. | Cyclic AMP | catabolite gene activator protein | Escherichia coli |
3 | Site-directed mutagenesis of the crp binding site provided evidence that this site is necessary for the in vivo regulation of ompB expression by cyclic AMP. | Cyclic AMP | catabolite gene activator protein | Escherichia coli |
4 | Control of the ompB operon by cyclic AMP-CRP may account for the observed regulation of the formation of OmpF and OmpC by this complex (N. W. Scott and C. R. Harwood, FEMS Microbiol. | Cyclic AMP | catabolite gene activator protein | Escherichia coli |