Title : Calmodulin binds to the C terminus of sodium channels Nav1.4 and Nav1.6 and differentially modulates their functional properties.

Pub. Date : 2003 Sep 10

PMID : 12967988






1 Functional Relationships(s)
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1 Analysis of calmodulin (CaM) binding to GST-fusion proteins containing the C-terminal domains of Nav1.1-Nav1.9 indicates that some of the tetrodotoxin-sensitive VGSC isoforms, including NaV1.4 and NaV1.6, are able to bind CaM in a calcium-independent manner. Tetrodotoxin sodium voltage-gated channel alpha subunit 4 Homo sapiens