Pub. Date : 2003 Sep 8
PMID : 12957710
11 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cytochrome c peroxidase (CcP) uses hydrogen peroxide as an electron acceptor to oxidize cytochrome c (Cc) in the mitochondrial intermembrane space. | Hydrogen Peroxide | cytochrome-c peroxidase | Saccharomyces cerevisiae S288C |
| 2 | Cytochrome c peroxidase (CcP) uses hydrogen peroxide as an electron acceptor to oxidize cytochrome c (Cc) in the mitochondrial intermembrane space. | Hydrogen Peroxide | cytochrome-c peroxidase | Saccharomyces cerevisiae S288C |
| 3 | Haploid yeast cells with the disrupted CCP1 gene were viable and able to grow in a medium containing lactic acid or glycerol as an energy source, indicating that CcP is not essential for both cell viability and respiration. | Lactic Acid | cytochrome-c peroxidase | Saccharomyces cerevisiae S288C |
| 4 | Haploid yeast cells with the disrupted CCP1 gene were viable and able to grow in a medium containing lactic acid or glycerol as an energy source, indicating that CcP is not essential for both cell viability and respiration. | Glycerol | cytochrome-c peroxidase | Saccharomyces cerevisiae S288C |
| 5 | However, CCP1-disrupted cells were more sensitive to H2O2 than wild-type cells. | Hydrogen Peroxide | cytochrome-c peroxidase | Saccharomyces cerevisiae S288C |
| 6 | We found that expression of CCP1 gene increases under respiratory culture conditions and by treatments with H2O2. | Hydrogen Peroxide | cytochrome-c peroxidase | Saccharomyces cerevisiae S288C |
| 7 | These results hint that the biological function of CcP is to reduce H2O2 generated during aerobic respiratory process. | Hydrogen Peroxide | cytochrome-c peroxidase | Saccharomyces cerevisiae S288C |
| 8 | Moreover, expression of CCP1 gene increased by treatments with peroxynitrite, indicating that CcP may act as a peroxynitrite scavenger. | Peroxynitrous Acid | cytochrome-c peroxidase | Saccharomyces cerevisiae S288C |
| 9 | Moreover, expression of CCP1 gene increased by treatments with peroxynitrite, indicating that CcP may act as a peroxynitrite scavenger. | Peroxynitrous Acid | cytochrome-c peroxidase | Saccharomyces cerevisiae S288C |
| 10 | Moreover, expression of CCP1 gene increased by treatments with peroxynitrite, indicating that CcP may act as a peroxynitrite scavenger. | Peroxynitrous Acid | cytochrome-c peroxidase | Saccharomyces cerevisiae S288C |
| 11 | Moreover, expression of CCP1 gene increased by treatments with peroxynitrite, indicating that CcP may act as a peroxynitrite scavenger. | Peroxynitrous Acid | cytochrome-c peroxidase | Saccharomyces cerevisiae S288C |