Title : Curcumin inhibits phorbol ester-induced expression of cyclooxygenase-2 in mouse skin through suppression of extracellular signal-regulated kinase activity and NF-kappaB activation.

Pub. Date : 2003 Sep

PMID : 12844482






2 Functional Relationships(s)
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1 Curcumin treatment attenuated TPA- stimulated NF-kappaB activation in mouse skin, which was associated with its blockade of degradation of the inhibitory protein IkappaBalpha and also of subsequent translocation of the p65 subunit to nucleus. Curcumin v-rel reticuloendotheliosis viral oncogene homolog A (avian) Mus musculus
2 Curcumin treatment attenuated TPA- stimulated NF-kappaB activation in mouse skin, which was associated with its blockade of degradation of the inhibitory protein IkappaBalpha and also of subsequent translocation of the p65 subunit to nucleus. Tetradecanoylphorbol Acetate v-rel reticuloendotheliosis viral oncogene homolog A (avian) Mus musculus