Title : Structure-activity relationships in a series of NPY Y5 antagonists: 3-amido-9-ethylcarbazoles, core-modified analogues and amide isosteres.

Pub. Date : 2003 Jun 16

PMID : 12781180






1 Functional Relationships(s)
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1 Efforts to replace the 3-amino-9-ethylcarbazole core, a known carcinogen, used the SAR generated in the carbazole series for guidance and led to the synthesis of a number of core-modified analogues. 3-amino-9-ethylcarbazole sarcosine dehydrogenase Homo sapiens