Pub. Date : 2003 Aug 15
PMID : 12738678
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We report in this paper that the DNA-binding drug mithramycin is a potent inducer of gamma-globin mRNA accumulation and fetal hemoglobin (HbF) production in erythroid cells from healthy human subjects and beta-thalassemia patients. | Plicamycin | hemoglobin subunit gamma 1 | Homo sapiens |
| 2 | We demonstrated that mithramycin was able to up-regulate preferentially gamma-globin mRNA production and to increase HbF accumulation, the percentage of HbF-containing cells, and their HbF content. | Plicamycin | hemoglobin subunit gamma 1 | Homo sapiens |