Title : Zoniporide: a potent and selective inhibitor of the human sodium-hydrogen exchanger isoform 1 (NHE-1).

Pub. Date : 2003 Spring

PMID : 12595915






1 Functional Relationships(s)
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1 In open chest, anesthetized rabbits, zoniporide also elicited a dose-dependent reduction in infarct size (ED(50) = 0.45 mg/kg/h) and inhibited NHE-1-mediated platelet swelling (93% inhibition at 4 mg/kg/h). zoniporide sodium/hydrogen exchanger 1 Oryctolagus cuniculus