Pub. Date : 2003 Apr 18
PMID : 12578836
10 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Properties of a mutant form of spermidine/spermine N(1)-acetyltransferase, L156F (L156F-SSAT), that is present in Chinese hamster ovary cells selected for resistance to the polyamine analogue N(1,) N(11)-bis(ethyl)norspermine (BE 3-3-3) were investigated. | Polyamines | diamine acetyltransferase 1 | Cricetulus griseus |
| 2 | Properties of a mutant form of spermidine/spermine N(1)-acetyltransferase, L156F (L156F-SSAT), that is present in Chinese hamster ovary cells selected for resistance to the polyamine analogue N(1,) N(11)-bis(ethyl)norspermine (BE 3-3-3) were investigated. | N(1),N(11)-diethylnorspermine | diamine acetyltransferase 1 | Cricetulus griseus |
| 3 | Increased K(m) values, decreased V(max) values, and decreased k(cat) values with both polyamine substrates, spermidine and spermine, indicated that L156F-SSAT is an inferior and less efficient acetyltransferase than wild-type SSAT. | Polyamines | diamine acetyltransferase 1 | Cricetulus griseus |
| 4 | Increased K(m) values, decreased V(max) values, and decreased k(cat) values with both polyamine substrates, spermidine and spermine, indicated that L156F-SSAT is an inferior and less efficient acetyltransferase than wild-type SSAT. | Polyamines | diamine acetyltransferase 1 | Cricetulus griseus |
| 5 | Increased K(m) values, decreased V(max) values, and decreased k(cat) values with both polyamine substrates, spermidine and spermine, indicated that L156F-SSAT is an inferior and less efficient acetyltransferase than wild-type SSAT. | Spermidine | diamine acetyltransferase 1 | Cricetulus griseus |
| 6 | Increased K(m) values, decreased V(max) values, and decreased k(cat) values with both polyamine substrates, spermidine and spermine, indicated that L156F-SSAT is an inferior and less efficient acetyltransferase than wild-type SSAT. | Spermidine | diamine acetyltransferase 1 | Cricetulus griseus |
| 7 | Increased K(m) values, decreased V(max) values, and decreased k(cat) values with both polyamine substrates, spermidine and spermine, indicated that L156F-SSAT is an inferior and less efficient acetyltransferase than wild-type SSAT. | Spermine | diamine acetyltransferase 1 | Cricetulus griseus |
| 8 | Increased K(m) values, decreased V(max) values, and decreased k(cat) values with both polyamine substrates, spermidine and spermine, indicated that L156F-SSAT is an inferior and less efficient acetyltransferase than wild-type SSAT. | Spermine | diamine acetyltransferase 1 | Cricetulus griseus |
| 9 | Only a 4-fold induction of L156F-SSAT activity resulted from the exposure of cells to the polyamine analogue, whereas wild-type SSAT was induced approximately 300-fold. | Polyamines | diamine acetyltransferase 1 | Cricetulus griseus |
| 10 | Only a 4-fold induction of L156F-SSAT activity resulted from the exposure of cells to the polyamine analogue, whereas wild-type SSAT was induced approximately 300-fold. | Polyamines | diamine acetyltransferase 1 | Cricetulus griseus |