Pub. Date : 2003
PMID : 12558458
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Many ESBL-producing organisms also express AmpC beta-lactamases and may be co-transferred with plasmids mediating aminoglycoside resistance. | Aminoglycosides | EsbL | Escherichia coli |
| 2 | In addition, there is an increasing association between ESBL production and fluoroquinolone resistance. | Fluoroquinolones | EsbL | Escherichia coli |
| 3 | Although in in vitro tests ESBLs are inhibited by beta-lactamase inhibitors such as clavulanic acid, the activity of beta-lactam/beta-lactamase inhibitor combination agents is influenced by the bacterial inoculum, dose administration regimen and specific type of ESBL present. | Clavulanic Acid | EsbL | Escherichia coli |
| 4 | Currently, carbapenems are regarded as the drugs of choice for treatment of infections caused by ESBL-producing organisms. | Carbapenems | EsbL | Escherichia coli |