Title : [Expression of heme oxygenase-1 and its effects in allergic airway inflammation and hyperresponsiveness].

Pub. Date : 2002 Nov

PMID : 12486335






1 Functional Relationships(s)
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1 The number of HO-1 positive cells was increased in the subepithelium of the bronchi after OVA challenge and HO-1 was localized to alveolar macrophage.Zinc-protoporphyrin (Zn-PP), a competitive inhibitor of hemeoxygenase, by intraperitoneal injection clearly inhibited AHR, pulmonary eosinophilia and IL-5 and IL-13 in the lung tissue. zinc protoporphyrin interleukin 13 Mus musculus