Title : Isolation and molecular characterization of a nelfinavir (NFV)-resistant human immunodeficiency virus type 1 that exhibits NFV-dependent enhancement of replication.

Pub. Date : 2003 Jan

PMID : 12477837






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 During the use of a phenotypic anti-human immunodeficiency virus type 1 (HIV-1) drug resistance assay in a large set of clinical virus isolates, we found a unique variant (CL-4) that exhibited a high level of nelfinavir (NFV) resistance and rather enhanced replication under subinhibitory concentrations of NFV (0.001 to 0.1 micro M). Nelfinavir endogenous retrovirus group W member 3 Homo sapiens