Title : Deletion of the glutamate carboxypeptidase II gene in mice reveals a second enzyme activity that hydrolyzes N-acetylaspartylglutamate.

Pub. Date : 2002 Oct

PMID : 12358725






1 Functional Relationships(s)
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1 The IC50 value for 2-PMPA was about 1 nm for wild-type brain membrane NAAG peptidase activity consistent with its activity against cloned ratand human GCPII, and 88 nm for the activity in brain membranes of the null mutants. 2-(phosphonomethyl)pentanedioic acid folate hydrolase 1 Homo sapiens