Title : The proprotein convertase PACE4 is upregulated by PDGF-BB in megakaryocytes: gene expression of PACE4 and furin is regulated differently in Dami cells.

Pub. Date : 2002 Jul

PMID : 12097169






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 PACE4 and furin are Ca(2+)-dependent serine endoproteases belonging to the subtilisin-like proprotein convertase (SPC) family. Serine proprotein convertase subtilisin/kexin type 6 Homo sapiens
2 In this study, we examined the expression of PACE4 and furin during the differentiation of megakaryoblastic cell lines, Dami and HEL cells, induced by phorbol 12-myristate 13-acetate (PMA). Tetradecanoylphorbol Acetate proprotein convertase subtilisin/kexin type 6 Homo sapiens
3 In this study, we examined the expression of PACE4 and furin during the differentiation of megakaryoblastic cell lines, Dami and HEL cells, induced by phorbol 12-myristate 13-acetate (PMA). Tetradecanoylphorbol Acetate proprotein convertase subtilisin/kexin type 6 Homo sapiens
4 The expression of PACE4 transcripts (both the PACE4A and PACE4C/CS isoforms) was upregulated more than 4-fold by PMA. Cesium proprotein convertase subtilisin/kexin type 6 Homo sapiens