Pub. Date : 2002 Sep 13
PMID : 12093808
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A minimal system of five purified proteins, hsp90, hsp70, Hop, hsp40, and p23, assembles glucocorticoid receptor (GR).hsp90 heterocomplexes and causes the simultaneous opening of the steroid binding cleft to access by steroid. | Steroids | DnaJ heat shock protein family (Hsp40) member B1 pseudogene 1 | Homo sapiens |
| 2 | A minimal system of five purified proteins, hsp90, hsp70, Hop, hsp40, and p23, assembles glucocorticoid receptor (GR).hsp90 heterocomplexes and causes the simultaneous opening of the steroid binding cleft to access by steroid. | Steroids | DnaJ heat shock protein family (Hsp40) member B1 pseudogene 1 | Homo sapiens |
| 3 | The first step in assembly is the ATP-dependent and hsp40 (YDJ-1)-dependent binding of hsp70 to the GR, which primes the receptor for subsequent ATP-dependent activation by hsp90, Hop, and p23 (Morishima, Y., Murphy, P. J. M., Li, D. P., Sanchez, E. R., and Pratt, W. B. | Adenosine Triphosphate | DnaJ heat shock protein family (Hsp40) member B1 pseudogene 1 | Homo sapiens |