Title : Ursodeoxycholic acid diminishes Fas-ligand-induced apoptosis in mouse hepatocytes.

Pub. Date : 2002 Jul

PMID : 12085348






2 Functional Relationships(s)
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1 TUDCA, 50 micromol/L (P <.001) and TCDCA up to 200 micromol/L (P <.0001) also reduced the hepatocytes apoptotic rate in Fas-L(-) cocultures. Taurochenodeoxycholic Acid Fas ligand (TNF superfamily, member 6) Mus musculus
2 In conclusion, UDCA, TUDCA, and TCDCA but not TCA are capable of protecting hepatocytes from Fas-L-induced apoptosis. Taurochenodeoxycholic Acid Fas ligand (TNF superfamily, member 6) Mus musculus