Title : Maleylacetoacetate isomerase (MAAI/GSTZ)-deficient mice reveal a glutathione-dependent nonenzymatic bypass in tyrosine catabolism.

Pub. Date : 2002 Jul

PMID : 12052898






4 Functional Relationships(s)
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1 There are well-described human diseases associated with deficiencies of all enzymes in this pathway except for maleylacetoacetate isomerase (MAAI), which converts maleylacetoacetate (MAA) to fumarylacetoacetate (FAA). maleylacetoacetate fumarylacetoacetate hydrolase Homo sapiens
2 There are well-described human diseases associated with deficiencies of all enzymes in this pathway except for maleylacetoacetate isomerase (MAAI), which converts maleylacetoacetate (MAA) to fumarylacetoacetate (FAA). maa fumarylacetoacetate hydrolase Homo sapiens
3 There are well-described human diseases associated with deficiencies of all enzymes in this pathway except for maleylacetoacetate isomerase (MAAI), which converts maleylacetoacetate (MAA) to fumarylacetoacetate (FAA). fumarylacetoacetate fumarylacetoacetate hydrolase Homo sapiens
4 A glutathione-mediated isomerization of MAA to FAA independent of MAAI enzyme was demonstrated in vitro. Glutathione fumarylacetoacetate hydrolase Homo sapiens