Title : Imperatoxin a enhances Ca(2+) release in developing skeletal muscle containing ryanodine receptor type 3.

Pub. Date : 2002 Mar

PMID : 11867448






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 [(3)H]ryanodine binding to RyR1 or RyR3 was significantly increased in the presence of IpTxa. [(3)h]ryanodine ryanodine receptor 3 Homo sapiens
2 Our data show that IpTxa can interact with both RyRs and that RyR3 is functional in myotubes and it can amplify the calcium release signal initiated by RyR1, perhaps through a calcium-induced mechanism. Calcium ryanodine receptor 3 Homo sapiens
3 Our data show that IpTxa can interact with both RyRs and that RyR3 is functional in myotubes and it can amplify the calcium release signal initiated by RyR1, perhaps through a calcium-induced mechanism. Calcium ryanodine receptor 3 Homo sapiens