Pub. Date : 2001 Jun
PMID : 11780430
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Angiotensin II type 1 receptor modulation of L-type calcium currents in guinea-pig ventricular cells. | Calcium | type-1 angiotensin II receptor | Cavia porcellus |
2 | 100 nmol/L Losartan, a specific AT1 receptor inhibitor, had no effect on ICa,L (n = 9), but the effect of Ang II on ICa,L was inhibited by 100 nmol/L Losartan. | Losartan | type-1 angiotensin II receptor | Cavia porcellus |
3 | CONCLUSION: Ang II stimulates ICa,L in guinea-pig ventricular cells by binding to AT1 through a transduction pathway involving protein kinase C. | isocyanic acid | type-1 angiotensin II receptor | Cavia porcellus |