Title : Angiotensin II type 1 receptor modulation of L-type calcium currents in guinea-pig ventricular cells.

Pub. Date : 2001 Jun

PMID : 11780430






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Angiotensin II type 1 receptor modulation of L-type calcium currents in guinea-pig ventricular cells. Calcium type-1 angiotensin II receptor Cavia porcellus
2 100 nmol/L Losartan, a specific AT1 receptor inhibitor, had no effect on ICa,L (n = 9), but the effect of Ang II on ICa,L was inhibited by 100 nmol/L Losartan. Losartan type-1 angiotensin II receptor Cavia porcellus
3 CONCLUSION: Ang II stimulates ICa,L in guinea-pig ventricular cells by binding to AT1 through a transduction pathway involving protein kinase C. isocyanic acid type-1 angiotensin II receptor Cavia porcellus