Title : Peptide inhibition of mammalian histidine decarboxylase.

Pub. Date : 1979 Oct

PMID : 117688






5 Functional Relationships(s)
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1 The hypothesis that N-terminal histidine peptides might act as inhibitors to histidine decarboxylase was investigated. Histidine histidine decarboxylase Homo sapiens
2 Histidine decarboxylase exclusively was inhibited by N-terminal histidine peptides. Histidine histidine decarboxylase Homo sapiens
3 Histidyl-phenylalanine was found to be about 100-fold as potent as the commonly used specific histidine decarboxylase inhibitor alpha-methyl histidine. histidylphenylalanine histidine decarboxylase Homo sapiens
4 Histidyl-phenylalanine was found to be about 100-fold as potent as the commonly used specific histidine decarboxylase inhibitor alpha-methyl histidine. alpha-methylhistidine histidine decarboxylase Homo sapiens
5 It is concluded that small peptides with histidine as the N-terminal amino acid might act as specific inhibitors for mammalian histidine decarboxylase. Histidine histidine decarboxylase Homo sapiens