Pub. Date : 2001 Nov 1
PMID : 11745426
17 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | MRP5 and SMRP is a candidate molecule for acquired Adriamycin resistance in addition to MDR1. | Doxorubicin | ATP binding cassette subfamily C member 5 | Homo sapiens |
| 2 | Induction of MRP5 and SMRP mRNA by adriamycin exposure and its overexpression in human lung cancer cells resistant to adriamycin. | Doxorubicin | ATP binding cassette subfamily C member 5 | Homo sapiens |
| 3 | Induction of MRP5 and SMRP mRNA by adriamycin exposure and its overexpression in human lung cancer cells resistant to adriamycin. | Doxorubicin | ATP binding cassette subfamily C member 5 | Homo sapiens |
| 4 | Induction of MRP5 and SMRP mRNA by adriamycin exposure and its overexpression in human lung cancer cells resistant to adriamycin. | Doxorubicin | ATP binding cassette subfamily C member 5 | Homo sapiens |
| 5 | Induction of MRP5 and SMRP mRNA by adriamycin exposure and its overexpression in human lung cancer cells resistant to adriamycin. | Doxorubicin | ATP binding cassette subfamily C member 5 | Homo sapiens |
| 6 | Increased expression of MDR1, MRP5 and SMRP mRNA was observed 48 hr after the initiation of Adriamycin exposure in human lung cancer PC-14 cells and cisplatin-resistant PC-14/CDDP cells, in a dose-dependent manner as measured by TaqMan real-time RT-PCR. | Doxorubicin | ATP binding cassette subfamily C member 5 | Homo sapiens |
| 7 | Increased expression of MDR1, MRP5 and SMRP mRNA was observed 48 hr after the initiation of Adriamycin exposure in human lung cancer PC-14 cells and cisplatin-resistant PC-14/CDDP cells, in a dose-dependent manner as measured by TaqMan real-time RT-PCR. | Doxorubicin | ATP binding cassette subfamily C member 5 | Homo sapiens |
| 8 | Increased expression of MDR1, MRP5 and SMRP mRNA was observed 48 hr after the initiation of Adriamycin exposure in human lung cancer PC-14 cells and cisplatin-resistant PC-14/CDDP cells, in a dose-dependent manner as measured by TaqMan real-time RT-PCR. | Cisplatin | ATP binding cassette subfamily C member 5 | Homo sapiens |
| 9 | Increased expression of MDR1, MRP5 and SMRP mRNA was observed 48 hr after the initiation of Adriamycin exposure in human lung cancer PC-14 cells and cisplatin-resistant PC-14/CDDP cells, in a dose-dependent manner as measured by TaqMan real-time RT-PCR. | Cisplatin | ATP binding cassette subfamily C member 5 | Homo sapiens |
| 10 | Increased expression of MDR1, MRP5 and SMRP mRNA was observed 48 hr after the initiation of Adriamycin exposure in human lung cancer PC-14 cells and cisplatin-resistant PC-14/CDDP cells, in a dose-dependent manner as measured by TaqMan real-time RT-PCR. | Cisplatin | ATP binding cassette subfamily C member 5 | Homo sapiens |
| 11 | To elucidate the relationship between Adriamycin resistance and MRP5 and SMRP, mRNA levels of MRP5 and SMRP in Adriamycin-resistant cell lines were compared with the parental cells. | Doxorubicin | ATP binding cassette subfamily C member 5 | Homo sapiens |
| 12 | To elucidate the relationship between Adriamycin resistance and MRP5 and SMRP, mRNA levels of MRP5 and SMRP in Adriamycin-resistant cell lines were compared with the parental cells. | Doxorubicin | ATP binding cassette subfamily C member 5 | Homo sapiens |
| 13 | These results suggest that subacute exposure of lung cancer cells to Adriamycin induced MRP5 and SMRP and that long-term exposure with Adriamycin selected the MRP5- and SMRP-overexpressing lung cancer cells. | Doxorubicin | ATP binding cassette subfamily C member 5 | Homo sapiens |
| 14 | These results suggest that subacute exposure of lung cancer cells to Adriamycin induced MRP5 and SMRP and that long-term exposure with Adriamycin selected the MRP5- and SMRP-overexpressing lung cancer cells. | Doxorubicin | ATP binding cassette subfamily C member 5 | Homo sapiens |
| 15 | These results suggest that subacute exposure of lung cancer cells to Adriamycin induced MRP5 and SMRP and that long-term exposure with Adriamycin selected the MRP5- and SMRP-overexpressing lung cancer cells. | Doxorubicin | ATP binding cassette subfamily C member 5 | Homo sapiens |
| 16 | These results suggest that subacute exposure of lung cancer cells to Adriamycin induced MRP5 and SMRP and that long-term exposure with Adriamycin selected the MRP5- and SMRP-overexpressing lung cancer cells. | Doxorubicin | ATP binding cassette subfamily C member 5 | Homo sapiens |
| 17 | MRP5 and SMRP is a candidate molecule for acquired Adriamycin resistance in addition to MDR1. | Doxorubicin | ATP binding cassette subfamily C member 5 | Homo sapiens |