Title : Hydrogen peroxide is a regulator of ABI1, a protein phosphatase 2C from Arabidopsis.

Pub. Date : 2001 Nov 23

PMID : 11728469






10 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Hydrogen peroxide is a regulator of ABI1, a protein phosphatase 2C from Arabidopsis. Hydrogen Peroxide Protein phosphatase 2C family protein Arabidopsis thaliana
2 ABI1 is a PP2C of Arabidopsis that exerts negative control on signalling of the phytohormone abscissic acid (ABA). Abscisic Acid Protein phosphatase 2C family protein Arabidopsis thaliana
3 ABI1 is a PP2C of Arabidopsis that exerts negative control on signalling of the phytohormone abscissic acid (ABA). Abscisic Acid Protein phosphatase 2C family protein Arabidopsis thaliana
4 Characterisation of the redox sensitivity of ABI1 revealed a strong enzymatic inactivation by hydrogen peroxide (H2O2) which has recently been implicated as a secondary messenger of ABA signalling. Hydrogen Peroxide Protein phosphatase 2C family protein Arabidopsis thaliana
5 Characterisation of the redox sensitivity of ABI1 revealed a strong enzymatic inactivation by hydrogen peroxide (H2O2) which has recently been implicated as a secondary messenger of ABA signalling. Hydrogen Peroxide Protein phosphatase 2C family protein Arabidopsis thaliana
6 Characterisation of the redox sensitivity of ABI1 revealed a strong enzymatic inactivation by hydrogen peroxide (H2O2) which has recently been implicated as a secondary messenger of ABA signalling. Abscisic Acid Protein phosphatase 2C family protein Arabidopsis thaliana
7 H2O2 reversibly inhibited ABI1 activity in vitro with an IC(50) of approximately 140 microM in the presence of physiological concentrations of glutathione. Hydrogen Peroxide Protein phosphatase 2C family protein Arabidopsis thaliana
8 H2O2 reversibly inhibited ABI1 activity in vitro with an IC(50) of approximately 140 microM in the presence of physiological concentrations of glutathione. Glutathione Protein phosphatase 2C family protein Arabidopsis thaliana
9 In addition, ABI1 was highly susceptible to inactivation by phenylarsine oxide (IC(50)=3-4 microM) indicative for the facile oxidation of vicinal cysteine residues. oxophenylarsine Protein phosphatase 2C family protein Arabidopsis thaliana
10 In addition, ABI1 was highly susceptible to inactivation by phenylarsine oxide (IC(50)=3-4 microM) indicative for the facile oxidation of vicinal cysteine residues. Cysteine Protein phosphatase 2C family protein Arabidopsis thaliana